GW4 has a number of high-spec, state-of-the-art facilities across its partner institutions that are technically supported and available for use by all our staff and students, search the list below for services or equipment.

Name Services Contact Categories Equipment
Exeter Centre for Cytomics
  • Advanced Multiparameter Cytometry
  • Full Spectral Flow Cytometry
  • Quantitative Imaging Flow Cytometry
  • Single Cell Genomic Cytometry
  • Fluorescence Activated Cell Sorting (FACS)
  • Luminex Multiplexing Assays
  • Complex Data Analysis (ML/AI)
  • Specialized Cytometry Training
  • Industrial/CRO conform Assays
  • Collaborations on Basic- & Applied Research
  • Consultancy

Dr Raif Yuecel & Dr Attila Bebes, cytometry@exeter.ac.uk

Exeter Centre for Cytomics

GW4 Facility for High-Resolution Electron Cryo-Microscopy
  •  Single Particle Analysis
  • Cryotomography
  • Suitable for Structural Biology and Soft Matter Nanomaterials
  • 200 kV X-FEG for generation of highly coherent electron beam
  • GATAN K2 Direct Electron Detector with Counting Mode capability and Zero Loss Peak energy filtering for high-resolution images
  • On-the-fly processing for monitoring and optimisation of data collection parameters

gw4-cryoem@bristol.ac.uk

GW4 Facility for High-Resolution Electron Cryo-Microscopy

Wales Positron Emission Tomography Imaging Centre (PETIC)
  • Clinical and Pre Clinical Services
  • FLT, FDG, FDOPA, Fallypride, Beta amyloid & Tau imaging
  • FDOPA and Fallypride quantification of dopaminergic transport and receptor function
  • NaF bone scanning
  • Gallium 68 DOTANOC imaging for neuroendocrine tumours
  • F Choline PET in Prostate Cancer
  • Monoclonal antibody imaging and kinetics
  • Stem Cell tracking

Chris Marshall

PETIC@cardiff.ac.uk

Wales Positron Emission Tomography Imaging Centre (PETIC)

Exeter Offshore testing facility
  • FaBTest has unique pre-consent for device demonstration
  • Full site survey and resource characteristics available
  • Test whole systems, sub-systems or numerical models

Lars Johanning

l.johanning@exeter.ac.uk

Exeter Offshore testing facility

Exeter Centre for Graphene Science
  • Graphene related device manufacture
  • Thin film deposition
  • E-beam lithography
  • Laserwriting

Mark Heath

m.heath@exeter.ac.uk

Exeter Centre for Graphene Science

Exeter Biosciences Sequencing facility
  • High throughput library preparation
  • Long read sequencing
  • Reduced representation sequencing (e.g. RAD-seq)
  • Amplicon sequencing
  • 16S/18S profiling
  • Denovo genome assembly

Konrad Paszkiewicz

biosciences-sequencing@exeter.ac.uk

Exeter Biosciences Sequencing facility

Cardiff X-ray Photoelectron Spectroscopy (XPS) analysis
  • XPS Analysis

David Morgan

MorganDJ3@cardiff.ac.uk

Cardiff X-ray Photoelectron Spectroscopy (XPS) analysis

Cardiff Transmission Electron Microscope
  • 3D tomography with high-stability goniometer stage
  • EDS elemental analysis with elemental mapping and line scan capability
  • CRYO imaging at -175 oC

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Transmission Electron Microscope

Cardiff Single Crystal X-ray diffraction
  • Dual wavelength, single crystal diffraction
  • Variable temperature diffraction measurements (80-500K)

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Single Crystal X-ray diffraction

Cardiff Scanning Electron Microscope
  • EBSD
  • EDX
  • SE, BS, STEM imaging

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Scanning Electron Microscope

Cardiff Powder X-ray diffraction

Variable temperature/room temperature powder X-ray diffraction measurements (16-300K)

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Powder X-ray diffraction

Cardiff Nuclear magnetic resonance

Acquisition of Small molecule and Biological molecule NMR data

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Nuclear magnetic resonance

Cardiff Mass spectrometry and chromatography
  • Generation of High Res and Low Res Mass Spectrometry data
  • HR GCMS, HR and LR LCMS, ICPMS
  • Quantitative determination of metals in solution/solids

Mahmoud Akhtar

akhtarm@cardiff.ac.uk

Cardiff Mass spectrometry and chromatography

Cardiff Gas Turbine Research Centre
  • Gas Analysis, NOx, CO, THC, O2, NH3
  • Particulates, LII, DMS
  • Laser diagnostics, LDA, PDA, PIV, PLIF
  • Chemiluminescence
  • High-Speed Videography
  • High-Fidelity Combustion Dynamics

Steve Morris

MorrisSM@cardiff.ac.uk

Cardiff Gas Turbine Research Centre

Cardiff Central Biotechnology Services (CBS)
  • Gene expression profiling
  • SNP genotyping and copy number analysis
  • MicroRNA analysis and methylation analysis
  • Evaluation of RNA quality
  • Large scale RT-PCR and TLDAs
  • Bioinformatics analysis
  • Primer and Project design and data analysis
  • Electrochemiluminescence
  • Flow Cytometry and cell sorting

Charlotte James

CBSadmin@cardiff.ac.uk

Cardiff Central Biotechnology Services (CBS)

Cardiff Bioimaging Research Hub
  • Histological sample processing and slide preparation service
  • Full training and support on all imaging systems
  • Confocal laser scanning microscopy with airyscanning technology, FLIM and FCS
  • Automated, high throughput, multiformat imaging with widefield, confocal and airyscan modalities
  • Spinning disc confocal microscopy
  • Lightsheet microscopy
  • In vivo fluorescence and bioluminescence imaging
  • Live cell imaging
  • Laser microdissection
  • Microfluorimetry
  • Conventional light microscopy (brightfield, darkfield, phase contrast, DIC, polarising, fluorescence, reflectance microscopy)
  • Whole slide imaging
  • Stereomicroscopy, microimaging and digital photography
  • Advanced image processing and analysis with machine learning
  • 3D printing service

Anthony Hayes (Facility manager) or Pete Watson (Academic lead for imaging)

bioimaginghub@cardiff.ac.uk

Cardiff Bioimaging Research Hub

Bristol X-ray Analytical Service
  • Single crystal X-ray structure determination (90-400K)
  • Variable temperature/room temperature powder X-ray diffraction measurements (16-300K)

Hazel Sparkes

hazel.sparkes@bristol.ac.uk

Bristol X-ray Analytical Service

Bristol Wolfson Bioimaging Facility
  • Latest-state-of-the-art Light and Electron Microscopy
  • Correlative Light Electron Microscopy (CLEM)
  • Cell & life sciences imaging for biological and biomedical research
  • Sample processing
  • Image analysis support

Mark Jepson

m.a.jepson@bristol.ac.uk

Bristol Wolfson Bioimaging Facility

Bristol Translational Biomedical Research Centre (TBRC)
  • Full medical, surgical and drug research on large animal models
  • High resolution MRI and surgical examination
  • Onsite anaesthetist

Stuart Pope

tbrc@bristol.ac.uk

Bristol Translational Biomedical Research Centre (TBRC)

Bristol Proteomics Facility
  • Protein Separation
  • Protein identification
  • Quantitative Proteomics (SILAC, TMT)
  • Phosphoproteomics
  • Serum Proteomics
  • Identification of protein binding partners

Kate Heesom

k.heesom@bristol.ac.uk

Bristol Proteomics Facility

Bristol MRC Integrative Epidemiology Unit Metabolomics NMR Facility
  • Quantitative, low volume metabolic measurement of human serum/EDTA-plasma
  • Metabolite profiling

Matt Goodwin

bristol-metabolomics@bristol.ac.uk

Bristol MRC Integrative Epidemiology Unit Metabolomics NMR Facility

Interface Analysis Centre (IAC)
  • Materials analysis
  • Facilities for the handling and analysis of radioactive specimens

Keith Hallam

k.r.hallam@bristol.ac.uk

Interface Analysis Centre (IAC)

Bristol Histology Services
  • Complete histological service
  • Fresh, fixed & frozen sectioning and staining
  • Wax processing
  • Immunocytochemistry & immunofluorencent staining
  • Image capture
  • Consultancy

Debbie Martin

debbie.martin@bristol.ac.uk

Bristol Histology Services

Bristol Electron Microbeam Laboratories
  • Quantitative X-ray microanalysis
  • X-ray mapping
  • Scanning electron microscopy and CL imaging

Stuart Kearns

Stuart.Kearns@bristol.ac.uk

Bristol Electron Microbeam Laboratories

Bristol Clinical Research and Imaging Centre (CRICBristol)
  • Siemens 3 Tesla MRI scanner and sleep laboratories
  • Studies in healthy volunteers and clinical populations
  • Full technical and training support

cric-contact@bristol.ac.uk

Bristol Clinical Research and Imaging Centre (CRICBristol)

Bristol Chemical NMR Facility
  • Solution state Nuclear Magnetic Resonance spectrometry of small molecules
  • Multinuclear and diffusion NMR
  • Molecular structure and mixture analysis

Craig Butts

Craig.Butts@bristol.ac.uk

Bristol Chemical NMR Facility

Bristol Chemical Mass Spectrometry Facility
  • HPLC-MS/UPLC-MS
  • LC-MSn
  • Nano-LC-MS
  • IMS-MS
  • Accurate mass, EI, CI, ESI, nanospray and MALDI MS

Paul Gates

Paul.Gates@bristol.ac.uk

Bristol Chemical Mass Spectrometry Facility

Bristol Chemical Imaging Facility
  • Fully-supported TEM
  • Range of sample holders and detectors for materials analysis
  • Fully-supported AFM installed in Cat 2 lab
  • Experiment design, sample preparation, image/spectra acquisition, data analysis

Sean Davis

S.A.Davis@bristol.ac.uk

Bristol Chemical Imaging Facility

Bristol Genomics Facility
  • Next generation sequencing
  • Microarray expression analysis
  • High throughput Genotyping
  • Real-time quantitative PCR
  • Capillary sequencing and genotyping
  • DNA and RNA analysis and quality assessment
  • Bioinformatic support

Jane Coghill or Christy Waterfall

genomics-facility@bristol.ac.uk

Bristol Genomics Facility

Bath Nanofabrication facility
  • Access to the facility to carry out own processing
  • Safety and equipment training and support is provided
  • Technical support for some sample fabrication

Stephen Wedge

nanofab@bath.ac.uk

Bath Nanofabrication facility

Bath Microscopy and analysis suite
  • Full image analysis
  • Light, scanning probe and electron microscopy
  • Full service package

Ursula Potter

U.J.Potter@bath.ac.uk

Bath Microscopy and analysis suite

Bath Material and Chemical Characterisation Facility (MC²)
  • Electron microscopy (SEM, TEM and cryo-FE-SEM)
  • Mass spectrometry coupled to gas- and liquid chromatography
  • Bio-imaging confocal microscopy and cell analysis
  • X-ray diffraction (Powder and single crystal)
  • Nuclear magnetic resonance spectroscopy (NMR)

Anneke Lubben

mc2@bath.ac.uk

Bath Material and Chemical Characterisation Facility (MC²)

Biological NMR Facility
  • High-field Nuclear Magnetic Resonance spectrometry
  • Protein and small molecule structure analysis
  • Protein-ligand binding studies

Matt Crump

Matt.Crump@bristol.ac.uk

NMR spectrometry

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Animal Behaviour Clinic
  • Behaviour consultation
  • Referring clinical cases
  • Residency programme
  • Separation related behaviours

Clinical Behaviour Office

Langford-behaviour@bristol.ac.uk

Veterinary Services, Animal welfare